منابع مشابه
Implantation potential of mosaic embryos.
Chromosomal mosaicism is a relatively common finding in human IVF embryos. However, the association between mosaicism in trophoectoderm and inner mass cells, the mechanisms involved, and its effects on implantation are far from established. We retrospectively reanalyzed array-CGH results from 1,362 trophoectoderm biopsies. We detected chromosomal mosaicism in 183 blastocysts (13.4%). A decrease...
متن کاملApproaches for prediction of the implantation potential of human embryos
Article info: Received: 9 November 2012 In revised form: 29 November 2012 Accepted: 30 November 2012 ABSTRACT Optimization of assisted reproductive technologies (ART) has become the main goal of contemporary reproductive medicine. The main aspiration of scientists working in the field is to use less intervention to achieve more, and, if possible, in a more cost-effective way. A number of direct...
متن کاملMelatonin upregulates ErbB1 and ErbB4, two primary implantation receptors, in pre-implantation mouse embryos
Objective(s): To evaluated the effects of melatonin on early embryo competence and the expression rate of the primary implantation receptors (ErbB1 and ErbB4). Materials and Methods: Two-cell mouse embryos were cultured in 3 groups: simple media, melatonin-treated (10-9 M melatonin) and Luzindole-treated (10-9 M luzindole). Then, the rate of ErbB1 and ErbB4 gene and protein expression, the leve...
متن کاملUterine Selection of Human Embryos at Implantation
Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first breach the endometrial epithelium and embed in the decidualizing stroma before being rejected via mechanisms that are poorly understood. Here we show that developmentally impaired human embryos elicit an endoplasmic stress response in hu...
متن کاملThe Effect of Melatonin on The Developmental Potential and Implantation Rate of Mouse Embryos
OBJECTIVE Melatonin is a scavenger agent that has been used to promote in vitro embryo development. This study was designed to show the effects of melatonin on the quality and quantity rate of preimplantation mouse embryo development and pregnancy. MATERIALS AND METHODS In this experimental study, super ovulated, mated mice were killed by cervical dislocation to collect two-cell zygotes from ...
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ژورنال
عنوان ژورنال: Systems Biology in Reproductive Medicine
سال: 2017
ISSN: 1939-6368,1939-6376
DOI: 10.1080/19396368.2017.1296045